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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="utf-8" />
<meta name="viewport" content="width=device-width, initial-scale=1" />
<meta name="theme-color" content="#000000" />
<meta
name="description"
content="Search for gene sets with gesel"
/>
<title>Gesel gene set search</title>
<link rel="stylesheet" href="styles.css">
</head>
<body>
<script type="module" src="./index.js"></script>
<h1>Bioconductor gene set search</h1>
<div id="species-input">
<label for="species-select">Choose species:</label>
<select name="species" id="species-select" onchange="window.setSpecies(this.value);">
<option value="9606">Human</option>
<option value="10090">Mouse</option>
<option value="7227">Fly</option>
<option value="10116">Rat</option>
<option value="6239">Worm</option>
<option value="7955">Zebrafish</option>
<option value="9598">Chimp</option>
</select>
</div>
<div class="row">
<div class="column">
<div class="option-box">
<label for="filter-genes">Search on genes of interest:</label>
<div class="textarea-wrapper">
<textarea id="filter-genes" class="input-textbox" placeholder="SNAP25 Neurod6 ATOH1 ENSG00000142208"></textarea>
</div>
<div class="option-description">
<p style="margin:0.25rem">
<em>Filter to sets that overlap any of the specified genes.</em>
</p>
<ul style="margin:0.25rem">
<li><em>Ensembl or Entrez IDs or gene symbols are supported.</em></li>
<li><em>One gene should be provided per line, any text after <code>#</code> will be ignored.</em></li>
<li><em>Sets will be ranked by the enrichment p-value in the output table.</em></li>
</ul>
<p style="margin:0.25rem">
<em>
Not sure if your gene identifiers are recognized by the database?
</em>
<button id="validate-genes" onclick="sanitizeGenes()"><em>Validate genes here!</em></button>
</p>
</div>
</div>
</div>
<div class="column">
<div class="option-box">
<label for="filter-text">Search on names/descriptions:</span>
<div class="textarea-wrapper">
<textarea id="filter-text" placeholder="pancrea* cancer" class="input-textbox"></textarea>
</div>
<div class="option-description">
<p style="margin:0.25rem">
<em>
Filter to sets with names or descriptions containing all search terms.
<code>*</code> and <code>?</code> wildcards are supported.
</em>
</p>
</div>
</div>
</div>
<div class="column">
<div class="option-box">
<label for="collection-availability">Restrict to collections:</label>
<form id="collection-availability">
</form>
<div class="option-description">
<p style="margin:0.25rem">
<em>
Filter to gene sets in the specified collections.
</em>
</p>
</div>
</div>
</div>
</div>
<div class="search-wrapper">
<button id="search" onclick="performSearch()">Search for gene sets</button>
</div>
<hr/>
<div style="padding:12px 15px">
<table class="result-table">
<thead>
<tr>
<th class="result-header-cell" style="width: 25%">Name</th>
<th class="result-header-cell" style="width: 35%">Description</th>
<th class="result-header-cell" style="width: 25%">Collection</th>
<th class="result-header-cell" style="width: 5%">Size</th>
<th class="result-header-cell" style="width: 5%">Overlap</th>
<th class="result-header-cell" style="width: 5%"><em>p</em>-value</th>
</tr>
</thead>
<tbody id="tabbody">
</tbody>
</table>
</div>
<div id="summary" class="footer"></div>
<div id="pages" class="footer" style="padding:0.5rem"></div>
</body>
</html>