diff --git a/src/NMRiumWrapper.tsx b/src/NMRiumWrapper.tsx
index e3cc3fa..9011e79 100644
--- a/src/NMRiumWrapper.tsx
+++ b/src/NMRiumWrapper.tsx
@@ -1,7 +1,7 @@
 import type { NMRiumChangeCb, NMRiumRefAPI } from 'nmrium';
 import { NMRium } from 'nmrium';
 import type { CSSProperties } from 'react';
-import { useCallback, useEffect, useRef } from 'react';
+import { useCallback, useEffect, useRef, useState } from 'react';
 import { RootLayout } from 'react-science/ui';
 
 import { LoadingIndicator } from './Loadingindicator.js';
@@ -18,9 +18,28 @@ const containerStyle: CSSProperties = {
   position: 'relative',
 };
 
+const ACCEPTED_ACTION_TYPES =
+  "'exportSpectraViewerAsBlob', 'selectTab', 'highlight', or 'clearHighlight'";
+
+function reportActionError(message: string) {
+  const error = new Error(message);
+  events.trigger('error', error);
+  // eslint-disable-next-line no-console
+  console.error(error);
+}
+
+const NO_HIGHLIGHTS: readonly string[] = [];
+
+function isStringArray(value: unknown): value is string[] {
+  return (
+    Array.isArray(value) && value.every((entry) => typeof entry === 'string')
+  );
+}
+
 export default function NMRiumWrapper() {
   const { allowedOrigins, isFetchAllowedOriginsPending } = useWhiteList();
   const nmriumRef = useRef<NMRiumRefAPI>(null);
+  const [highlightedIds, setHighlightedIds] = useState(NO_HIGHLIGHTS);
   const {
     workspace,
     preferences,
@@ -78,9 +97,24 @@ export default function NMRiumWrapper() {
             setActiveTab({ tab: tab.toUpperCase() });
             break;
           }
+          case 'highlight': {
+            const ids: unknown = request.params?.ids;
+            if (!isStringArray(ids)) {
+              reportActionError(
+                "ERROR! Property 'params.ids' must be an array of strings.",
+              );
+              break;
+            }
+            setHighlightedIds(ids);
+            break;
+          }
+          case 'clearHighlight': {
+            setHighlightedIds(NO_HIGHLIGHTS);
+            break;
+          }
           default: {
-            throw new Error(
-              `ERROR! Property 'type' accepts only 'exportViewerAsBlob'.`,
+            reportActionError(
+              `ERROR! Property 'type' accepts only ${ACCEPTED_ACTION_TYPES}.`,
             );
           }
         }
@@ -133,6 +167,7 @@ export default function NMRiumWrapper() {
         state={data?.state}
         aggregator={data?.aggregator}
         onChange={dataChangeHandler}
+        highlightedIds={highlightedIds}
         preferences={preferences}
         workspace={workspace}
         emptyText={defaultEmptyMessage}
diff --git a/src/demo/NMRiumWrapperDemo.tsx b/src/demo/NMRiumWrapperDemo.tsx
index 00388e3..00615be 100644
--- a/src/demo/NMRiumWrapperDemo.tsx
+++ b/src/demo/NMRiumWrapperDemo.tsx
@@ -6,6 +6,7 @@ import NMRiumWrapper from '../NMRiumWrapper.js';
 import events from '../events/event.js';
 import { loadFilesFromURLs } from '../utilities/loadFilesFromURLs.js';
 
+import qmSignalsData from './data/qm-signals.json' with { type: 'json' };
 import jsonData from './data/test.json' with { type: 'json' };
 
 const Container = styled.div`
@@ -105,6 +106,42 @@ export default function NMRiumWrapperDemo() {
         >
           Test Logger
         </Button>
+        <Button
+          className="load-qm-signals-btn"
+          style={{ marginRight: '10px' }}
+          onClick={() => {
+            events.trigger('load', {
+              data: qmSignalsData as unknown as NMRiumData,
+              type: 'nmrium',
+            });
+          }}
+        >
+          Test load QM signals
+        </Button>
+        <Button
+          className="highlight-signal-btn"
+          style={{ marginRight: '10px' }}
+          onClick={() => {
+            events.trigger('action-request', {
+              type: 'highlight',
+              params: {
+                ids: ['qm-signal-1H-7-8', 'qm-range-1H-7-8', 'qm-1H-7-8'],
+              },
+            });
+          }}
+        >
+          Test highlight signal
+        </Button>
+        <Button
+          className="clear-highlight-btn"
+          onClick={() => {
+            events.trigger('action-request', {
+              type: 'clearHighlight',
+            });
+          }}
+        >
+          Clear highlight
+        </Button>
       </Header>
 
       <NMRiumWrapper />
diff --git a/src/demo/data/qm-signals.json b/src/demo/data/qm-signals.json
new file mode 100644
index 0000000..55c9675
--- /dev/null
+++ b/src/demo/data/qm-signals.json
@@ -0,0 +1 @@
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ifts":[{"atom":1,"prediction":18.1,"status":"accept"},{"atom":2,"prediction":58.3,"status":"accept"}]}}]}}
\ No newline at end of file
diff --git a/src/events/types.ts b/src/events/types.ts
index 4227d51..585c380 100644
--- a/src/events/types.ts
+++ b/src/events/types.ts
@@ -35,6 +35,17 @@ type ActionRequest =
   | {
       type: 'selectTab';
       params: { tab: string };
+    }
+  | {
+      type: 'highlight';
+      /**
+       * Ids passed to NMRium's `highlightedIds`, for example peak, range or
+       * signal ids. Replaces the previous host highlight.
+       */
+      params: { ids: string[] };
+    }
+  | {
+      type: 'clearHighlight';
     };
 
 interface ActionResponse {
diff --git a/test-e2e/core.test.ts b/test-e2e/core.test.ts
index 59c4d79..e4b985f 100644
--- a/test-e2e/core.test.ts
+++ b/test-e2e/core.test.ts
@@ -3,6 +3,8 @@ import { expect, test } from '@playwright/test';
 import NmriumWrapperPage from './NmriumWrapperPage.js';
 import triplinineData from './data/Triplinine.json' with { type: 'json' };
 
+const HIGHLIGHTED_FILL = '#ff6f0057';
+
 async function testLoadStructure(nmrium: NmriumWrapperPage) {
   // Open the "Chemical structures" panel.
   await nmrium.page.click('div >> text=Chemical structures');
@@ -124,3 +126,136 @@ test('should load test-data.nmrium file', async ({
 
   await nmrium.checkSpectraTabsIsVisible(['1H', '13C', '1H,1H', '1H,13C'])
 });
+
+async function postActionRequest(
+  nmrium: NmriumWrapperPage,
+  data: Record<string, unknown>,
+) {
+  await nmrium.page.evaluate((data) => {
+    window.postMessage({ type: 'nmr-wrapper:action-request', data }, '*');
+  }, data);
+}
+
+async function loadQmSignals(nmrium: NmriumWrapperPage) {
+  await nmrium.page.click('text=Test load QM signals');
+  await nmrium.checkSpectraTabsIsVisible(['1H', '13C']);
+  await expect(nmrium.page.getByTestId('range').first()).toBeVisible();
+}
+
+// The tab that opens after loading differs between browsers.
+async function show1HTab(nmrium: NmriumWrapperPage) {
+  await postActionRequest(nmrium, {
+    type: 'selectTab',
+    params: { tab: '1H' },
+  });
+  await expect(
+    nmrium.page.locator('.tab-list-active').getByText('1H', { exact: true }),
+  ).toBeVisible();
+}
+
+function highlightedRanges(nmrium: NmriumWrapperPage) {
+  return nmrium.page.locator(
+    `[data-testid="range"] rect[fill="${HIGHLIGHTED_FILL}"]`,
+  );
+}
+
+function highlightedPeaks(nmrium: NmriumWrapperPage) {
+  return nmrium.page.locator('g.peaks path[stroke-width="3px"]');
+}
+
+test('should highlight a peak by id via nmr-wrapper:action-request', async ({
+  page,
+}) => {
+  const nmrium = await NmriumWrapperPage.create(page);
+  await loadQmSignals(nmrium);
+  await show1HTab(nmrium);
+
+  await postActionRequest(nmrium, {
+    type: 'highlight',
+    params: { ids: ['qm-1H-9'] },
+  });
+
+  await expect(highlightedPeaks(nmrium)).toHaveCount(1);
+  await expect(highlightedRanges(nmrium)).toHaveCount(0);
+
+  await postActionRequest(nmrium, { type: 'clearHighlight' });
+
+  await expect(highlightedPeaks(nmrium)).toHaveCount(0);
+});
+
+test('should highlight a signal with its range and peak by ids', async ({
+  page,
+}) => {
+  const nmrium = await NmriumWrapperPage.create(page);
+  await loadQmSignals(nmrium);
+  await show1HTab(nmrium);
+
+  await postActionRequest(nmrium, {
+    type: 'highlight',
+    params: { ids: ['qm-signal-1H-7-8', 'qm-range-1H-7-8', 'qm-1H-7-8'] },
+  });
+
+  await expect(highlightedRanges(nmrium)).toHaveCount(1);
+  await expect(highlightedPeaks(nmrium)).toHaveCount(1);
+
+  await postActionRequest(nmrium, { type: 'clearHighlight' });
+
+  await expect(highlightedRanges(nmrium)).toHaveCount(0);
+  await expect(highlightedPeaks(nmrium)).toHaveCount(0);
+});
+
+test('should keep the highlight when selectTab is sent right before it', async ({
+  page,
+}) => {
+  const nmrium = await NmriumWrapperPage.create(page);
+  await loadQmSignals(nmrium);
+  await show1HTab(nmrium);
+
+  await postActionRequest(nmrium, {
+    type: 'selectTab',
+    params: { tab: '13C' },
+  });
+  await postActionRequest(nmrium, {
+    type: 'highlight',
+    params: { ids: ['qm-signal-13C-2', 'qm-range-13C-2', 'qm-13C-2'] },
+  });
+
+  await expect(
+    nmrium.page.locator('.tab-list-active').getByText('13C'),
+  ).toBeVisible();
+  await expect(highlightedRanges(nmrium)).toHaveCount(1);
+  await expect(highlightedPeaks(nmrium)).toHaveCount(1);
+});
+
+test('should emit nmr-wrapper:error when highlight ids are invalid', async ({
+  page,
+}) => {
+  const nmrium = await NmriumWrapperPage.create(page);
+  await loadQmSignals(nmrium);
+  await show1HTab(nmrium);
+
+  const errorMessage = page.evaluate(
+    () =>
+      new Promise<string>((resolve) => {
+        window.addEventListener('message', (event) => {
+          if (event.data?.type === 'nmr-wrapper:error') {
+            resolve(String(event.data.data?.message ?? event.data.data));
+          }
+        });
+      }),
+  );
+
+  await postActionRequest(nmrium, {
+    type: 'highlight',
+    params: { ids: 'qm-1H-9' },
+  });
+
+  expect(await errorMessage).toContain('params.ids');
+
+  await postActionRequest(nmrium, {
+    type: 'highlight',
+    params: { ids: ['qm-1H-9'] },
+  });
+
+  await expect(highlightedPeaks(nmrium)).toHaveCount(1);
+});